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phenobarbital will minimize the extent or effect of olanzapine/samidorphan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Robust CYP3A4 inducers lessen amounts of olanzapine and samidorphan by~50% and ~75% respectively.Contraindications to pentobarbital use involve prior hypersensitivity reactions to

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